Magnesium Matters: Which Type Is Right for You?
- randrson
- Jun 20, 2025
- 3 min read
Updated: Jul 18, 2025

Magnesium is an essential mineral involved in over 300 biochemical reactions in the body, including muscle function, energy production, sleep regulation, and stress response. But not all magnesium supplements are created equal. With so many forms on the market, it can be confusing to know which one is best for your needs.
In this post, we’ll break down the most common types of magnesium supplements, what they’re used for, and how to choose the right one for you.
🌿 Why Supplement Magnesium?
Magnesium deficiency is more common than you think — caused by stress, poor diet, medication use (like PPIs or diuretics), or chronic illness. Symptoms of low magnesium can include:
Muscle cramps or twitching
Anxiety or irritability
Sleep disturbances
Constipation
Fatigue
Headaches
Supplementing with the right form of magnesium can support your health in a targeted way.
🔍 Common Forms of Magnesium & What They’re Good For:
🧘♀️ Magnesium Glycinate
Best for: Sleep, anxiety, muscle relaxation
Why it works: Magnesium is bound to glycine, an amino acid that promotes calming neurotransmitters in the brain.
Gentle on the stomach and rarely causes diarrhea.
Ideal for people with insomnia, anxiety, chronic stress, or fibromyalgia.
💩 Magnesium Citrate
Best for: Occasional constipation, general supplementation
Why it works: It draws water into the intestines to help soften stools.
May also improve mild magnesium deficiency.
Watch out: Can cause loose stools at higher doses.
💪 Magnesium Malate
Best for: Energy production, muscle pain, fibromyalgia
Why it works: Malic acid supports ATP (energy) production in cells.
Often used by people with chronic fatigue or muscle soreness.
💭 Magnesium Threonate
Best for: Brain health, memory, cognitive support
Why it works: It crosses the blood-brain barrier, making it unique for supporting neuroplasticity and cognition.
Popular for those managing brain fog, age-related memory loss, or mental clarity.
❤️ Magnesium Taurate
Best for: Heart health, blood pressure, calming the nervous system
Why it works: Taurine helps regulate heart rhythm and reduces blood pressure.
Often used for cardiovascular support and stress-related heart symptoms (like palpitations).
🦴 Magnesium Oxide
Best for: Occasional constipation, short-term use
Why it works: Has a strong laxative effect and is inexpensive.
Poorly absorbed, so not ideal for long-term supplementation or correcting deficiency.
🦠 Magnesium Chloride
Best for: General absorption, topical use (e.g. magnesium oil)
Why it works: Readily absorbed and often used in magnesium sprays or baths.
Can be taken orally, but more commonly used transdermally.
🧴 Bonus: Topical Magnesium (Lotions & Sprays)
If you experience localized muscle tension or restless legs, topical magnesium (often magnesium chloride) can be applied directly to sore areas. This can be especially useful for people who have digestive sensitivity to oral forms.
⚠️ Who Should Be Cautious with Magnesium?
People with kidney disease (magnesium builds up when kidneys don’t filter well)
If you are on medications like bisphosphonates, antibiotics, or diuretics, talk to your provider about timing and interactions.
High doses of some forms (especially citrate or oxide) can cause diarrhea or cramping.
✅ Bottom Line: Choose the Right Form for Your Needs
Symptom/Goal | Best Form |
Sleep & Anxiety | Magnesium Glycinate |
Constipation | Magnesium Citrate or Oxide |
Energy & Muscle Pain | Magnesium Malate |
Cognitive Support | Magnesium Threonate |
Heart Health | Magnesium Taurate |
Topical Relief | Magnesium Chloride |
🩺 Want Help Finding the Right Supplement?
At Cascade Mind & Body Clinic, we guide you toward the supplements that support your whole health, not just symptom management. We now offer Thorne® medical-grade supplements—including magnesium—in clinic or through our online dispensary or at 🛒 Fullscript® with access to hundreds on online brands. 📅 Book a consultation🌐 Visit: www.cascademidbodyclinic.com📍 Located in 145 SW 6th Street Redmond, Oregon💬 Call us: 541-699-6128
📚 Citations:
DiNicolantonio, J. J., O’Keefe, J. H., & Wilson, W. (2018). Subclinical magnesium deficiency: A principal driver of cardiovascular disease and a public health crisis. Open Heart, 5(1), e000668. https://doi.org/10.1136/openhrt-2017-000668
Volpe, S. L. (2013). Magnesium in disease prevention and overall health. Advances in Nutrition, 4(3), 378S–383S. https://doi.org/10.3945/an.112.003483
Barbagallo, M., & Dominguez, L. J. (2010). Magnesium and aging. Current Pharmaceutical Design, 16(7), 832–839. https://doi.org/10.2174/138161210790883615
Kirkland, A. E., Sarlo, G. L., & Holton, K. F. (2018). The Role of Magnesium in Neurological Disorders. Nutrients, 10(6), 730. https://doi.org/10.3390/nu10060730
Walker, A. F., Marakis, G., Christie, S., & Byng, M. (2009). Mg citrate found more bioavailable than other magnesium preparations in a randomised, double-blind study. Magnesium Research, 16(3), 183–191.
Rosanoff, A., Weaver, C. M., & Rude, R. K. (2012). Suboptimal magnesium status in the United States: Are the health consequences underestimated? Nutrition Reviews, 70(3), 153–164. https://doi.org/10.1111/j.1753-4887.2011.00465.x
Wang, J., Um, P., Dickerman, B. A., & Liu, J. (2017). Magnesium intake and mortality due to liver diseases: Results from the NHANEhttps://pubmed.ncbi.nlm.nih.gov/29263344/S III follow-up study. American Journal of Clinical Nutrition, 105(2), 392–399. https://doi.org/10.3945/ajcn.116.139733




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